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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related cataract
ncRNA name hsa-miR-34a-5p
ncRNA Category miRNA
Disease name age-related cataract
Species Homo sapiens
Tissues/Cell_line lens epithelium; human lens epithelial cell line HLE-B3
Methods MTT assay, flow cytometry, Hoechst staining, qRT-PCR, microarray, Western blot, fluorescence in situ hybridization (FISH)
Expression pattern up-regulated
Functional description In the clinical specimens, the miRNA’s abundance increases as the LOCSIII grading climbs.
PubMed ID 29653565
Year 2018
Title Identification of H2O2 induced oxidative stress associated microRNAs in HLE-B3 cells and their clinical relevance to the progression of age-related nuclear cataract.
Drug-related ncRNA NO

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